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Search Result

Search Results for " cytochrome p450-c "

Targets

P450 c-Met/HGFR

10

Compounds

5

Natural Products

6

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T6260 AMG-208 AMG 208 P450 , c-Met/HGFR
AMG-208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.
T1290 Oxiconazole nitrate Ro 13-8996 Others , Antibiotic , Antifection , Antifungal
Oxiconazole nitrate (Ro 13-8996) is the nitrate salt form of oxiconazole, a broad spectrum imidazole derivative with antifungal activity. Although the exact mechanism of action has yet to be fully elucidated, oxiconazole...
T9335 1,1'-Methylenedi-2-naphthol Squoxin Others
1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human).
T10953 Dafadine-A P450
Dafadine-A is an analog of dafadine and a novel inhibitor of DAF-9 cytochrome P450 in the nematode Caenorhabditis elegans. Mammalian orthologs that also inhibit DAF-9 (CYP27A1).
TP2238 Cytochrome P450 CYP1B1 (190-198) [Homo sapiens] Others
Cytochrome P450 CYP1B1 (190-198) [Homo sapiens] is a peptide from Cytochrome c, which is a small heme protein found loosely associated with the inner membrane of the mitochondrion. Cytochromes c from certain eukaryotes, ...
T36662 Imidafenacin Metabolite M4 Imidafenacin Metabolite M4
Imidafenacin metabolite M4 is a metabolite of the muscarinic acetylcholine receptor antagonist imidafenacin.1It is formed from imidafenacin by the cytochrome P450 (CYP) isoform CYP3A4. 1.Kanayama, N., Kanari, C., Masuda,...
T35730 Clindamycin Sulfoxide
Clindamycin sulfoxide is an active metabolite of the antibiotic clindamycin . It is formed via S-oxidation of clindamycin primarily by the cytochrome P450 (CYP) isoform CYP3A4. Clindamycin sulfoxide inhibits the growth o...
T37839 20-hydroxy Prostaglandin E2 20-hydroxy Prostaglandin E2
20-hydroxy Prostaglandin E2 (20-hydroxy PGE2) is a product of cytochrome P450 metabolism of PGE2 . ω-Oxidation at C-20 followed by β-oxidation and the loss of up to four carbons from the lower side chain is a prominent m...
T36215 17R(18S)-EpETE
17R(18S)-EpETE is an oxylipin and a cytochrome P450 metabolite of eicosapentaenoic acid .1,217R(18S)-EpETE is an activator of large-conductance calcium-activated potassium (BKCa) channels, increasing the potassium curren...
T35463 (±)14(15)-EET (±)14,15-EET,(±)14,15-EpETrE,(±)14(15)-EET
(±)14(15)-EET is a metabolite of arachidonic acid that is formed via epoxidation of arachidonic acid by cytochrome P450.[1],[2] It prevents increases in leukotriene B4, ICAM-1, and chemokine (C-C motif) ligand 1 (CCL2) i...
Cat No. Product Name Synonyms Targets
T3149 Salvianolic Acid C Others , P450
Salvianolic Acid C is extracted from the root of Salvia miltiorrhiza, a perennial plant in the genus Salvia.
T2770 Gentiopicroside Gentiopicrin P450 , HCV Protease
Gentiopicroside (Gentiopicrin), a naturally occurring iridoid glycoside, extracted from Gentiana manshurica Kitag, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; has antianti-inflammatorya...
T3811 Ginsenoside C-K Ginsenoside compound K,Ginsenoside K P450 , cell cycle arrest , COX , NO Synthase
Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.
T1548 Methoxsalen NCI-C55903,Xanthotoxin,8-Methoxypsoralen,8-MOP P450 , DNA
Methoxsalen (NCI-C55903) is a Photoactivated Radical Generator and Psoralen. The mechanism of action of methoxsalen is as a Photoabsorption. The physiologic effect of methoxsalen is by means of Photosensitizing Activity.
T6S0923 Hypericin Hypericine,Cyclosan Apoptosis , Antiviral , Influenza Virus , Tyrosine Kinases , Antibacterial , PKC
1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL...

Natural Products

Salvianolic Acid C
T3149
Synonym:
Target: Others, P450
Gentiopicroside
T2770
Synonym: Gentiopicrin
Target: P450, HCV Protease
Ginsenoside C-K
T3811
Synonym: Ginsenoside compound K,Ginsenoside K
Target: P450, cell cycle arrest, COX, NO Synthase
Methoxsalen
T1548
Synonym: NCI-C55903,Xanthotoxin,8-Methoxypsoralen,8-MOP
Target: P450, DNA
Hypericin
T6S0923
Synonym: Hypericine,Cyclosan
Target: Apoptosis, Antiviral, Influenza Virus, Tyrosine Kinases, Antibacterial, PKC

Recombinant Proteins

Species：
Human (6)
Expression System：
HEK293 Cells (3)
E. coli (2)
P. pastoris (Yeast) (1)
Tag：
C-His-Avi (3)
N-6xHis (3)
Cat No. Product Name Species Expression System
TMPH-01182 CYP1A1 Protein, Human, Recombinant (His) Human E. coli
CYP1A1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 63.7 kDa and the accession number is P04798.
TMPH-02141 CYP21A2 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-d...
TMPH-02140 CYP21A2 Protein, Human, Recombinant (E. coli, His) Human E. coli
A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-d...
TMPK-01456 HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01450 HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01451 HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
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